NCBI Studies and Information

We strongly encourage you to do additional research to determine which CBD products are best for you. Due to FDA regulations, we cannot share all of the benefits of cannabidiol, but we can link to reputable, third-party resources that can.  The links below will open up sites outside of hellobluecbd.com in a new tab. If you have any questions, please don’t hesitate to click the blue bubble in the lower right corner to chat with us, or send a message through our contact page.

The Endocannabinoid System

Pacher P, Bátkai S, Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev. 2006;58(3):389-462. doi:10.1124/pr.58.3.2

Anxiety Relief

Blessing EM, Steenkamp MM, Manzanares J, Marmar CR. Cannabidiol as a Potential Treatment for Anxiety Disorders. Neurotherapeutics. 2015;12(4):825-836. doi:10.1007/s13311-015-0387-1

Bergamaschi MM, Queiroz RH, Chagas MH, et al. Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. Neuropsychopharmacology. 2011;36(6):1219-1226. doi:10.1038/npp.2011.6

Crippa JA, Guimarães FS, Campos AC, Zuardi AW. Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age. Front Immunol. 2018;9:2009. Published 2018 Sep 21. doi:10.3389/fimmu.2018.02009

Pain Relief

Ryz NR, Remillard DJ, Russo EB. Cannabis Roots: A Traditional Therapy with Future Potential for Treating Inflammation and Pain. Cannabis Cannabinoid Res. 2017;2(1):210-216. Published 2017 Aug 1. doi:10.1089/can.2017.0028

Topical Applications (Muscle Butter)

Chen J, Jiang QD, Chai YP, Zhang H, Peng P, Yang XX. Natural Terpenes as Penetration Enhancers for Transdermal Drug Delivery. Molecules. 2016;21(12):1709. Published 2016 Dec 11. doi:10.3390/molecules21121709

Sports Performance

McCartney D, Benson MJ, Desbrow B, Irwin C, Suraev A, McGregor IS. Cannabidiol and Sports Performance: a Narrative Review of Relevant Evidence and Recommendations for Future Research. Sports Med Open. 2020;6(1):27. Published 2020 Jul 6. doi:10.1186/s40798-020-00251-0

General Use in Therapy and Psychiatry

Calapai G, Mannucci C, Chinou I, et al. Preclinical and Clinical Evidence Supporting Use of Cannabidiol in Psychiatry. Evid Based Complement Alternat Med. 2019;2019:2509129. Published 2019 Aug 29. doi:10.1155/2019/2509129

Elsaid S, Kloiber S, Le Foll B. Effects of cannabidiol (CBD) in neuropsychiatric disorders: A review of pre-clinical and clinical findings. Prog Mol Biol Transl Sci. 2019;167:25-75. doi: 10.1016/bs.pmbts.2019.06.005. Epub 2019 Aug 28. PMID: 31601406.

Bonaccorso S, Ricciardi A, Zangani C, Chiappini S, Schifano F. Cannabidiol (CBD) use in psychiatric disorders: A systematic review. Neurotoxicology. 2019 Sep;74:282-298. doi: 10.1016/j.neuro.2019.08.002. Epub 2019 Aug 11. PMID: 31412258.

Mandolini GM, Lazzaretti M, Pigoni A, Oldani L, Delvecchio G, Brambilla P. Pharmacological properties of cannabidiol in the treatment of psychiatric disorders: a critical overview. Epidemiol Psychiatr Sci. 2018 Aug;27(4):327-335. doi: 10.1017/S2045796018000239. Epub 2018 May 23. PMID: 29789034; PMCID: PMC6998871.

Calapai G, Mannucci C, Chinou I, et al. Preclinical and Clinical Evidence Supporting Use of Cannabidiol in Psychiatry. Evid Based Complement Alternat Med. 2019;2019:2509129. Published 2019 Aug 29. doi:10.1155/2019/2509129